2 PhD Positions in Developmental Biology (m/f/d) – Emmy Noether Group, Dr. Ali Seleit

2 PhD Positions in Developmental Biology (m/f/d) – Emmy Noether Group, Dr. Ali Seleit

NEU

Teilzeit

Forschung und Lehre

The Centre for Integrative Biological Signaling Studies (CIBSS) and the Faculty of Biology at the University of Freiburg are pleased to announce two open PhD positions in the newly founded Emmy-Noether funded research group of Dr. Ali Seleit. The lab focu 2 PhD Positions in Developmental Biology (m/f/d) – Emmy Noether Group, Dr. Ali Seleit

Bewerbungsfrist: 30. April 2026

Veröffentlichungsdatum: 3. April 2026

Eintrittstermin: 1. Juni 2026

Arbeitsumfang: Part-time position (65 %)

Kennziffer: 00004923

Beschreibung

Project Description

The successful candidates will drive independent research projects supported by the prestigious

DFG Emmy-Noether Programme. Both PhD candidates will focus on projects utilizing the Japanese rice fish, Oryzias latipes (medaka) and related species, to further our understanding of the fundamental mechanisms underlying the control of developmental timing in vertebrates.

Key methodologies in the lab include:

Genome editing: CRISPR/Cas9 microinjections in Oryzias species to generate knock-in

(KI) lines and knock-outs (Crispants)

Genetic hybridization: hybrid F1 and F2 families from different Oryzias species

Multi-omics: scRNAseq, proteomics and metabolic profiling of Oryzias species

Genomic analysis: building and annotating genomes of Oryzias species

Advanced Imaging: 4D-confocal and light-sheet imaging of fluorescently tagged

endogenous proteins during embryonic development in Oryzias species

Required Qualifications:

A Masters degree (or equivalent) in Biology, Molecular Medicine, Genetics, or a closely

related field.

Hands-on experience with standard molecular biology techniques (e.g., PCR, gel

electrophoresis, molecular cloning and DNA/RNA sequencing).

Basic coding and computational data analysis skills (e.g., Python/R/Imaris/Fiji)

Strong critical thinking skills, high intrinsic motivation, and an independent, well-organized

work style.

Highly Encouraged (but not required):

Previous experience working with aquatic model systems (medaka, zebrafish, killifish).

Experience with advanced light microscopy and quantitative image analysis.

Experience with sequencing library preparation (DNA/RNA) or advanced computational

data analysis (e.g. scRNAseq, proteomics, de-novo genome assembly and annotation).

What We Offer:

A fully funded DFG Emmy-Noether PhD position (65% E13) for 36 months, with the

possibility of extension.

A dynamic, collaborative, and interdisciplinary research environment within the CIBSS

Cluster of Excellence and the Faculty of Biology at the University of Freiburg.

Opportunities to contribute to cutting-edge research in developmental genetics and

vertebrate biology.

Supportive mentorship and training in advanced molecular, genomic, and imaging

techniques.

Integration into the Spemann Graduate School of Biology and Medicine (SGBM) at the

University of Freiburg, offering structured thesis advisory committees and career

development opportunities.

Further information on the lab you can find:

How to apply:

Please submit your complete application in English – including a cover letter detailing your

research interests and motivation, a CV, relevant transcripts/certificates, and the contact details of two academic references – as a single PDF document.

The position is limited to 31. Mai 2029. The salary will be determined in accordance with E13 TV-L.

We will be particularly pleased to receive applications from women for the position advertised here.