Postdoctoral Position (m/f/d) in Hematology / Oncology Research

We are recruiting for a newly established DFG Emmy Noether Research Group at the Division of Pediatric Hematology and Oncology.

Postdoctoral Position (m/f/d) in Hematology / Oncology Research

We are recruiting for a newly established DFG Emmy Noether Research Group at the Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, working at the interface of leukemia biology, translational metabolomics and ribosome profiling. The group is embedded in a high-profile collaborative environment spanning the DKTK (German Cancer Consortium) partner site Freiburg and DKFZ Heidelberg. This environment offers an exceptional platform to build a strong scientific profile in translational AML research.

Our research addresses one of the unmet clinical needs in oncology: understanding how acute myeloid leukemia (AML) cells survive and persist under therapeutic stress, and how this chemoresistance can be therapeutically disrupted. Using cutting-edge approaches including ribosome profiling, single-cell analysis, metabolomics, in vivo models and patient-derived xenografts (PDX), we dissect the metabolic and translational programs that drive treatment resistance and clonal heterogeneity in AML, in close collaboration with leading national and international partners in the field.

We are looking for an outstanding and highly motivated postdoctoral researcher who wants to take a leading role in shaping this research program, with the opportunity to develop their scientific profile, mentor doctoral students, and contribute to important publications.

We offer:

a unique opportunity to help shape and grow a newly funded Emmy Noether group at the interface of leukemia research, metabolic approaches and translational oncology

Integration into the University Medical Center Freiburg and German Cancer Consortium network, providing access to leading expertise, infrastructure and collaborative opportunities across one of Europes recognized cancer research consortia

a state-of-the-art laboratory and access to core facilities at the University Medical Center and DKFZ Heidelberg

scientific independence combined with close mentorship, and the chance to actively define your own research questions

a clear pathway for career development, including training, grant-writing support and mentoring

Your Tasks:

Design and lead experiments using ribosome and polysome profiling workflows, metabolic profiling, functional cell-based assays and drug sensitivity assays

Design an conduct in vivo experiments in (patient-derived xenograft) mouse models

Analyze and interpret multi-omic sequencing data using established pipelines, in close collaboration with bioinformaticians

take responsibility for laboratory safety and contribute to the supervision and training of doctoral students

actively contribute to manuscript preparation, grant applications and the scientific direction of the group

Your profile:

Doctorate in biology, biochemistry, molecular medicine, or a related field, ideally with a strong publication record

excellent background in cell and molecular biology, with a strong interest in translational cancer research

Documented experience with cell culture, functional cell-based assays and animal models

a highly motivated, independent, collaborative and diligent working style, with ambition to grow into scientific leadership

professional working proficiency in English

Employment will be on a limited-term basis (36 months) with the possibility of extension. Salary