Post-doctoral researcher (m/f/d)

Primary Duties & Responsibilities:

Make key contributions to the ERC Starting Grant funded project “PerturbPhos” (Grant agreement ID: 101222284), developing ultra-sensitive mass spectrometry (MS)-based phosphoproteomics technologies to study how drugs affect a patients tumor proteome

Build and optimize a scalable phosphoproteomics platform tailored to high-dimensional perturbation experiments of primary cells

Analyze large-scale (phospho)proteomics datasets using R or Python-based computational tools to integrate prior knowledge and characterize drug-induced phosphorylation changes

Work and communicate efficiently across inter-professional teams

Disseminate project results through presentations and manuscripts.

Required Skills & Qualifications:

PhD in (bio)chemistry, molecular biology, systems biology, or a related field

Theoretical knowledge and practical skills in mass spectrometry-based proteomics, ideally with hands-on experience in low-input phosphoproteomics

Demonstrated experience with mammalian cell culture and sample preparation for MS analysis

Ability to independently develop and troubleshoot MS-based proteomics workflows

Prior experience with clinical patient material and/or characterizing small molecule drugs is desired

Proficiency in R or Python for analyzing omics datasets, including statistical analysis and integration of multiple datatypes

Strong track record of scientific excellence (e.g., high-quality first-author publications), rigorous research practice, and commitment to research integrity

Strong ability work and communicate effectively in interdisciplinary teams (clinicians, biologists, bioinformaticians)

Strong scientific writing and presentation skills in English.

We offer you even more:

Classification is based on TV-L in pay grade E13 if the personal and collective agreement requirements are met.

Reference number: DM20/2026

* Limited to 24 months, with an option to extend

Regardless of origin, age, gender or disability - you are welcome here at Jena University Hospital.